Rheumatoid Arthritis Symptoms in Hands, Knees, and Feet Explained
Rheumatoid Arthritis (RA) most commonly affects the joints of the hands, knees, and feet, leading to pain, stiffness, and reduced function. Since these joints are vital for everyday activities such as walking, gripping, and movement, RA can significantly impact quality of life. At IRIS Clinics, we see many patients who first notice RA symptoms in these specific areas, making early recognition essential for treatment and management.
RA is not caused by aging or overuse, but by the immune system mistakenly attacking the joint lining (synovium). Over time, this causes chronic inflammation that erodes cartilage and bone. If left untreated, it can result in joint deformities, loss of mobility, and severe pain.
Understanding how RA manifests in the hands, knees, and feet is critical. At IRIS Clinics, specialized diagnostic imaging and rheumatology expertise help detect early joint changes and guide patients toward personalized treatment for long-term relief.
Symptoms vary depending on which joints are affected, but generally include persistent stiffness (especially in the morning), visible swelling, tenderness, and warmth around the joints. These signs usually appear symmetrically, meaning both sides of the body are affected equally.
The progression of symptoms can be different for each patient. While some experience sudden flare-ups, others notice gradual worsening over time. That’s why regular monitoring at IRIS Clinics, along with advanced imaging techniques like ultrasound and MRI, is recommended for accurate tracking of disease activity.
RA Symptoms in Key Joints
Here’s how RA typically presents in the most commonly affected joints:
1. Hands
- Swelling and stiffness in the finger joints and wrists.
- Difficulty gripping objects or performing fine motor tasks.
- In advanced cases, fingers may begin to drift outward (ulnar deviation).
2. Knees
- Persistent pain, stiffness, and swelling around the knees.
- Difficulty bending or straightening the knees fully.
- In severe RA, knees may feel unstable or produce a grinding sensation.
3. Feet
- Pain and tenderness in the toes and ankles.
- Swelling makes wearing shoes uncomfortable.
- Long-term RA may cause deformities such as bunions, hammertoes, or flat feet.
At IRIS Clinics, treatment is customized to target the affected joints and prevent irreversible damage. With a combination of medications, physiotherapy, and lifestyle planning, patients can maintain mobility and reduce pain, even in advanced stages.




